B-Immune

Coronavirus: What You Need to Know

The type of coronavirus responsible for causing COVID-19 is part of a family of viruses that affect both humans and
animals. This family of viruses is also responsible for conditions as simple as the common cold, and as severe as the SARS virus, which can cause respiratory distress and even death.

This new type of coronavirus, catalogued as COVID-19, causes a respiratory disease with ‘CO’ standing for corona and ‘VI’ standing for virus, and ‘D’ for disease.

You may have seen the word “novel” in reference to this type of coronavirus, and that simply means that it’snew–we’ve never seen it before. While there is a vaccine in development for COVID-19, it’s unlikely it will be widely available anytime soon.

Coronavirus has an incubation period of anywhere from 2 to 14 days, with most quarantines lasting between 10 and 14 days if someone is suspected of having been exposed, or showing symptoms (1).An incubation period is the measurement of time it usually takes for an individual to develop symptoms for an illness.

What Does COVID-19 Do?

COVID-19 is primarily a respiratory virus, affecting the airways and respiratory system, although a diverse array of symptoms have been reported, including loss of taste and fatigue, which can linger much after the initial infection has passed.

Once infected, the virus binds t certain cells in the lungs that normally prevent the buildup of mucus and other debris within the lungs. This can cause some difficulty breathing, and can result in the need for intubation to assist proper oxygen flow.

When you’re infected with any virus, your immune system will mount an appropriate response to the invaders and begi to kill off the virus cells. You may develop a fever, which creates a hostile environment for the virus, and you’ll gradually get rid of mucus and buildup by coughing, and through your nose running. This is a completely normal immune response.

The Cytokine Storm

The problem is that for those with compromised immune function, this stage can trigger an inflammatory response known as acute respiratory distress syndrome (ARDS), where the immune system overreacts and begins to damage the body’s own tissues (2).

This has commonly been called a cytokine storm, and the mortality rate from COVID-19 ARDS can be as high as 40% to 50% (2).

Am I at Risk for COVID-19?

For about 80% of people who contract COVID-19, it will cause a variety of symptoms, which range from mild to severe, and resolve (2). However, as you get older, and if you have underlying health conditions, your risk of hospitalization with COVID-19 increases.

The most common underlying health conditions which increase risk for COVID-19 complications are cardiovascular disease (32%), diabetes (30%), and chronic lung disease (18%) (3).

The CDC estimates that 8 out of every 10 COVID-19 related deaths occur in individuals 65 years or older, although there have been a number of deaths in younger, healthy individuals which raises concern for risk also (4)

How COVID-19 Spreads

As new information becomes available about the transmission of COVID-19, research shows that this virus is more contagious when spread through respiratory droplets in the air than through contact with an infected surface (5).

This means that coughing, sneezing, close talking, and being in a confined space with those carrying COVID-19 increases the risk of spread.

Precautions

While there is no way to ensure completely that you won’t be affected by COVID-19, these integrative medicine tips from our holistic medical center will help your immune system to be in optimal condition.

  • Get consistent and adequate rest.

It’s no secret that lack of sleep makes you more susceptible to illness. Sleep switches on your body’s adaptive immune response, helping it to trap invading pathogens and process them out of the body (6).

  • Avoid immune-damaging foods.

Foods such as refined sugar, alcohol, and processed grains create excess inflammation and can slow a healthy immune response.

Instead, focus on nutrient-dense and colorful fruits and veggies, such as spinach, broccoli, beets, and carrots; antioxidant-rich fruits such as berries, papaya, and pineapple; quality proteins, and healthy fats such as avocado, coconut, and omega-3s from salmon and other fish.

  • Stay home if you’re sick

Staying home when you’re unwell is just as much for your benefit as those around you. You never know who else may be immune compromised, or recovering from another cold or flu that can make them susceptible to the germs you may be spreading when you’re out and about.

  • Wear a mask.

Wearing a mask reduces the amount of respiratory droplets spread into the air from person to person (7)(8). By reducing the amount of respiratory droplets in the air, we also reduce the spread of virus cells contained in those droplets.

  • Wash your hands and keep them away from your face.

Coronavirus can be neutralized through effective hand-washing, and by alcohol-based hand sanitizers with greater than 60 percent alcohol content. Hand washing should be the go-to though, with hand sanitizer use being a last resort where water isn’t available.

  • Avoid travel to restricted regions.

Currently, several countries remain closed to international travel, which is for good as it restricts the spread of Covid-19.

Should I Wear a Mask?

Wearing a mask reduces the spread of respiratory droplets coming from a person’s nose and mouth if they suspect or are experiencing an illness.

The fewer respiratory droplets released into the air, the less likely other people are to come in contact with germs and become sick themselves.

Wearing a mask protects those around you by limiting respiratory droplets you spread into the environment.

Supplements for Immune Support

To maximize immune support, incorporate some of these functional nutrients to make sure your immune system is in top shape.

Vitamin C

Ascorbic acid is known to function as an antioxidant by savaging ROS, and a number of studies have suggested that
vitamin C supplementation can impact the immune system. Moreover, in vitro and in vivo studies in avians have shown that vitamin C could be protective against avian coronavirus infection, and human trials have found that vitamin C may decrease susceptibility to viral respiratory infections and pneumonia.
2 High doses of ascorbic acid reduce the severity and duration of symptoms from the common cold, which is caused by rhinovirus.3 Studies of vitamin C for the treatment of hospitalized and critically ill patients have shown mixed results on mortality, length of stay in the intensive care unit, and duration of mechanical ventilation.4 However, high doses of intravenous vitamin C were generally safe.

Daily dose of 1000-2000mg in divided dose per day

Vitamin D

Vitamin D is found in foods such as dairy products, cereals, and oily fish, and is converted to its biologically active form 25-hydroxyvitamin D in the skin through the effect of ultraviolet B radiation on 7-dehydrocholesterol. In vitro, vitamin D has immunomodulatory effects (including inhibition of antigen-presenting cells), antiproliferative effects on T cells, modulating expression and secretion of type 1 interferon, and inhibition of proinflammatory cytokine expression (IL-6 and TNF alpha).7

Deficiency of vitamin D is common, with studies showing approximately 40% of the US population to be vitamin D deficient, especially during the winter season. Factors such as older age, corticosteroid use, and darker skin are associated with lower concentrations of 25-hydroxyvitamin D, putting these patient populations at higher risk for vitamin D deficiency. Vitamin D deficiency has been associated with a higher incidence of acute respiratory infections, with a hypothesized link between the seasonality of influenza and vitamin D deficiency. Intriguingly, vitamin D deficiency in calves was associated with an increased susceptibility to infection with bovine coronavirus,2
which may have implications for COVID-19 infection in humans. 
A number of randomized trials have evaluated the effect of vitamin D supplementation for the prevention of acute respiratory infections. In a meta-analysis, vitamin D supplementation decreased the incidence of acute respiratory infection.8 In subgroup analyses, the protective effect of vitamin D was greater in patients with baseline serum 25-hydroxyvitamin D concentrations < 25 nmol/L (vs ≥ 25 nmol/L) and isolated to those receiving daily dosing (vs bolus dosing).8 In light of these data, a recent article recommended that patients at risk for COVID-19 consider starting daily vitamin D supplementation to raise serum 25-hydroxyvitamin D concentrations in order to reduce the risk for infection.7 Supplement with 1000 to 5000 IUs daily.

Zinc

Zinc is known to be important for immune function and has a role in antibody and white blood cell production. Deficiency of zinc increases pro-inflammatory cytokine (IL-1, IL-6, and TNF alpha)concentrations and decreases the production of antibodies, while zinc supplementation has been shown to increase the ability of polymorphonuclear
cells to fight infection.
2 Zinc has also been implicated in coronavirus biology, with increasing intracellular concentrations of zinc demonstrated to inhibit virus RNA polymerase activity and viral replication in an in vitro and cell culture model of severe acute respiratory syndrome coronavirus 1 (SARS-CoV-1).5 In a meta-analysis evaluating studies comparing zinc supplementation and placebo, high-dose zinc reduced the duration but not the severity of symptoms of the common cold.6 Overall adverse effects and specifically nausea were significantly more
frequent with zinc (which may have been dose-dependent), and the effect of prophylactic zinc supplementation was inconclusive. Whether zinc supplementation can benefit patients with lower respiratory tract infections such as COVID-19 is unclear. Because of its role in immune function and potential to decrease coronavirus replication, zinc is currently being investigated for prophylaxis and treatment of patients with COVID-19. 
Daily dose of 45-50mg per day in divided dose.

 

B-IMMUNE

1. In viral cases like Covid, Vit C 1000-2000mg , Vit D3 1000-4000 iu, Zinc 45-50mg per day has been found effective to boost immunity 

2. B-IMMUNE has all these things in proper dose combination

3. So 2 tablets of B-IMMUNE/ day gives Vit C ~ 900mg, VitD3 2000I.U. , Zinc 45 mg 

4. Also at 9.5/tab it’s COST EFFECTIVE FOR PATIENT as compared to giving individual components separately

5. Since patients with other chronic conditions like CVD, Obese, Diabetes are at very high risk of mortality due to Covid 19, it becomes essential for these patients to have stronger Immunity, thus B-IMMUNE is required

6. And since many of patients are asymptomatic, it makes sense to Rx B-IMMUNE to prevent health deterioration in patients having other co morbid conditions

You can find full-spectrum immune support in B-IMMUNE, containing antioxidant vitamin C, Vitamin D, and the immune supportive power of zinc–all in one simple supplement.

The Way Forward with Integrative Medicine

Illness can be scary. But much of what causes panic is a lack of information and understanding. The most important thing to do is keep a level head and evaluate data as it becomes available. The best thing we can all do is be prudent with our actions to avoid spreading any germs, and to make smart decisions to build a robust immune system.

Share the valuable information with someone who needs it. Knowledge is power.

Resources1.

https://www.unicef.org/indonesia/coronavirus

  1. https://www.who.int/news-room/q-a-detail/q-a-coronaviruses
  2. https://www.cdc.gov/flu/about/burden/index.html
  3. https://www.journalofhospitalinfection.com/article/S0195-6701(20)30046-3/fulltext?mobileUi=0
  4. https://www.cdc.gov/coronavirus/2019-ncov/travelers/index.html
  5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183890/
  6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166406/
  7. https://www.ncbi.nlm.nih.gov/pubmed/22695229

Resources Supplement

  1. Zhang L, Liu Y. Potential interventions for novel
    coronavirus in China: a systematic review. J Med Virol 2020;
    92(5):479–490.
    http://doi.org/10.1002/jmv.25707. Accessed June 2, 2020.

2.
Hemilä H, Chalker E. Vitamin C
for preventing and treating the common cold. Cochrane Database Syst Rev 2013;
2013(1). doi:10.1002/14651858.CD000980.pub4

3.
Carr AC. Vitamin C administration
in the critically ill: a summary of recent meta-analyses. Crit Care 2019;
23(1):265. doi:10.1186/s13054-019-2538-y

4.
teVelthuis AJW, van den Worm SHE,
Sims AC, Baric RS, Snijder EJ, van Hemert MJ. Zn2+ inhibits
coronavirus and arterivirus RNA polymerase activity in vitro and zinc
ionophores block the replication of these viruses in cell culture. PLoSPathog
2010; 6(11). doi:10.1371/journal.ppat.1001176

5.
Singh M, Das RR. Zinc for the
common cold. Cochrane Database Syst Rev 2013; 2013(6):CD001364.
doi:10.1002/14651858.CD001364.pub4

6.
Grant WB, Lahore H, McDonnell SL, et
al. Evidence that vitamin D supplementation could reduce risk of influenza
and COVID-19 infections and deaths. Nutrients 2020; 12(4):988.
doi:10.3390/nu12040988

7.
Martineau AR, Jolliffe DA, Hooper
RL, et al. Vitamin D supplementation to prevent acute respiratory tract
infections: systematic review and meta-analysis of individual participant data.
BMJ 2017; 356. doi:10.1136/bmj.i6583